1. In patients with end-stage ankle osteoarthritis, no difference was observed in outcomes between total ankle replacement (TAR) and ankle fusion (AF) surgeries. 2. There were no significant differences in the rate of adverse events in patients who received ART compared to AF surgeries. Level of evidence assessment: 1 (Excellent) Summary of the study: Surgical …
1. Early mobilization of patients after mechanical ventilation in the intensive care unit (ICU) did not lead to an improvement in the number of days alive and out of hospital. 2. Early mobilization was associated with more adverse events than routine care. Level of evidence assessment: 1 (Excellent) Overview of the study: Patients with severe …
1. A randomized controlled trial found that pretreatment with vitamin D supplementation did not reduce the risk of statin-associated muscle symptoms in adult patients. 2. Vitamin D supplementation also did not reduce the risk of statin discontinuation. Assessment of the level of proof: 1 (Excellent) Summary of the study: Statins are among the most commonly …
