Summary: Plaque formation can cause spheroid-shaped swellings to build up along axons near amyloid plaque deposits. The swellings are caused by lysosomes, which digest cellular waste. As the swelling grows, it can block the transmission of signals from one area of the brain to another. Source: Yale The formation of amyloid plaques in the brain …
Summary: Researchers have identified a protein that could be harnessed to help microglia in the brain ward off Alzheimer’s disease and other neurodegenerative diseases. Source: The conversation Many neurodegenerative diseases, or conditions resulting from the loss of function or death of brain cells, remain largely incurable. Most available treatments target only one of the multiple …
Following Healthcare Buzz’s initial October article – “What is Long COVID”, including the various symptoms that are difficult to identify and treat – many people replied “thank you for reassuring me that these lingering symptoms are not not in my head”. The frustration of finding any kind of treatment for the wide array of symptoms …
Health Care Buzz: Long COVID Series – Patient Story 3 Read More »
In a large study, the experimental drug lecanemab was able to slow Alzheimer’s disease, but not stop it. Some researchers believe that the drug will become the first to help many patients; others have questions. Cemile Bingol/Getty Images hide caption toggle caption Cemile Bingol/Getty Images In a large study, the experimental drug lecanemab was able …
Is lecanemab the drug against Alzheimer’s disease that will finally make a difference? Read More »
Many neurodegenerative diseases, or conditions resulting from the loss of function or death of brain cells, remain largely incurable. Most available treatments target only one of the multiple processes that can lead to neurodegeneration, which may not be effective in treating symptoms or disease progression completely, if at all. But what if researchers harnessed the …
Arming the brain’s ‘maintenance’ cells could help stave off Alzheimer’s disease Read More »
Despite the decades and billions of dollars invested in the study of Alzheimer’s disease, some aspects of its development remain stubbornly mysterious. Researchers have followed many leads, from gum disease to autoimmune diseases. The original (and now controversial) hypothesis that amyloid plaques play a central role in disease emergence seemed like a promising way forward, …
New discovery could explain why we’ve been misled about the cause of Alzheimer’s disease Read More »
Talk about food for thought. A growing body of research suggests that ultra-processed foods like frozen pizzas and breakfast cereals high in sugars, fats and empty calories are bad for your health. Now, a new large-scale study presented at the 2022 Alzheimer’s Association International Conference in San Diego this week offers more evidence that people …
A new lab test has been developed to measure levels of beta-amyloid oligomers in blood samples, which can be used to predict future diagnoses of Alzheimer’s disease. Overall, patients today are diagnosed with Alzheimer’s Alzheimer’s disease is a disease that attacks the brain, leading to a decline in mental abilities that worsens over time. It …
New blood test can detect ‘toxic’ proteins years before Alzheimer’s symptoms appear Read More »
The experimental drug lecanemab showed a 27% slowing of the progression of cognitive decline in patients with early-stage Alzheimer’s disease, according to a study published this week in the New England Journal of Medicine. “These results show that lecanemab shows promise for people with early-stage Alzheimer’s disease, with a significant slowing of decline and a …
Experimental Alzheimer’s drug may slow disease progression, but there are risks: experts Read More »
An as yet unapproved drug shows promise for reducing cognitive decline in patients with Alzheimer’s disease. Whether it might work to prevent disease progression is the question in a new clinical trial of lecanemab, a monoclonal antibody developed by Japanese pharmaceutical company Eisai and Biogen of Massachusetts. Michigan’s only site, at the University of Michigan …
Drug study to examine Alzheimer’s disease prevention, research Michigan participants Read More »
